Vesicles. Macular vs Papular Rash: Changes in the skin color or consistency without any elevation from the skin level are known as macules. A nodule is a circumscribed elevation of the skin larger than a papule (1 cm). Vesicle: Well circumscribed fluid-filled lesion up to 5-10mm. - The technical umbrella term is usually "bullous", rather than "vesicular" dermatitis/eruptions. Vesicles are small, fluid-filled sacs that can appear on your skin. Overview. It can appear in a variety of shapes, colors, and sizes. Margins of the lesion are elevated. - "Vesicles" and "bullae" works for an expert audience. The first and most common is single or localized lesions. Maculopapular rash may be mistakenly called macule, papule, patch, nodule, plaque, vesicle, or pustule. (>10mm bulla) (herpes, varicella) Wheal or hive: A localized edematous plaque-like lesion, somewhat irregular and transient. Vesicular lesions (Table 132.11) can be considered in three clinical categories. A papule is a raised white lesion that is essentially less than 0.5cm in diameter. A papule is a raised area of skin tissue that’s less than 1 centimeter around. A papule can have distinct or indistinct borders. Remember: Changes with size Changes with depth Macules patches Erosion ulcer Papules plaques (or nodules) Vesicles … Picture 12: Macule measures less than 1 cm. 10 An example is anthrax, with its evolving cutaneous lesion from painless papule to ulcer with surrounding vesicles. Photo from Wright State University Dermatology Plaques may result from a coalescence of papules. The fluid inside these vesicles may be clear, white, yellow, or mixed with blood. -papule -plaque -nodule -tumor -vesicle -bulla -pustule -cyst Secondary Lesions -scale -crust -excoriation -lichenification -maceration -fissure -erosion -ulcer Distinct Lesions -wheal/hive -burrow -comedone -atrophy -keloid -fibrosis -petechiae -telangiectasis -milium: Papule. Cyst — papule or nodule that contains fluid or semi-fluid material so is fluctuant. They often extend into the dermis, and may be due to inflammatory, neoplastic, or metabolic in origin. These include macules, papules, nodules, plaques, vesicles, bullae, pustules, and wheals. -papule -plaque -nodule -tumor -vesicle -bulla -pustule -cyst Secondary Lesions -scale -crust -excoriation -lichenification -maceration -fissure -erosion -ulcer Distinct Lesions -wheal/hive -burrow -comedone -atrophy -keloid -fibrosis -petechiae -telangiectasis -milium: Vesicle. It is a flat blemish like that of a freckle. To differentiate these skin lesions from each other, here are the pictures of each. Plaque — a circumscribed, palpable lesion more than 1 cm in diameter; most plaques are elevated. Vesicles are tiny sacs that transport material within or outside the cell. 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